您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 品牌 > Sigma-Aldrich > β2-微球蛋白 来源于人类尿液

β2-Microglobulin from human urine

β2-微球蛋白 来源于人类尿液

品牌
Sigma-Aldrich
货号
SAE0112
规格纯度
≥98% (SDS-PAGE), solution
参考价格
1601.22 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
β2-Microglobulin from human urine
β2-微球蛋白 来源于人类尿液
产品介绍:

产品说明

应用

β2-Microglobulin from human urine was used to test humoral CSF parameters in the differential diagnosis of hematologic CNS neoplasia. It was also used in the identification of CTL epitopes in hepatitis C virus by a genome-wide computational scanning and a rational design of peptide vaccine.

生化/生理作用

β2 microglobulin (β2-M) is a polypeptide that associates with the heavy chain of class I major histocompatibility complex (MHC) antigens on the cell surface. The interaction is dynamic and plays a critical role in the stability of the MHC antigens and their ability to present peptide antigens in CD8+ cells. A transient complex of MHC heavy chain and β2-M is known to be assembled into the TAP molecule (transporter associated with antigen processing) through interactions with a number of chaperones. Binding of processed peptide releases the Class I-β2-M complex to the cell surface. Absence of binding leads to degradation in the proteasome.

制备说明

Prepared by the method of Berggard and Bearn.

基本信息

MDL编号MFCD00130615

产品性质

测定≥98% (SDS-PAGE)
形式solution
UniProt登记号P61769
储存温度−20℃
Gene Informationhuman ... B2M(567)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

推荐产品