Belinostat

产品名称：

866323-14-0
Belinostat
(2E)-N-Hydroxy-3-[3-(phenylsulfamoyl)phenyl]prop-2-enamide
PX-105684
PXD101
PXD 101
(E)-N-Hydroxy-3-(3-(N-phenylsulfamoyl)phenyl)acrylamide
PX 105684
PX105684
(2E)-N-Hydroxy-3-[3-[(phenylamino)sulfonyl]phenyl]-2-propenamide
PXD-101

产品介绍：

产品说明

生化/生理作用

Belinostat (PX105684; PXD101) is a potent, hydroxamate class pan-selective histone deacetylases (HDACs) inhibitor (IC50: class I HDAC1/2/3/8 = 41/125/30/216 nM, class IIA HDAC4/7/9 = 115/67/128 nM, class IIB HDAC6 = 82 nM) with anti-cancer efficacy in vitro and in vivo.

基本信息

经验(实验)分子式	C₁₅H₁₄N₂O₄S
分子量	318.35
MDL编号	MFCD08064035

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 2 mg/mL, clear
储存温度	−20℃

安全信息

象形图
警示用语：	Danger
危险声明	H340 - H361f - H373
预防措施声明	P201 - P202 - P260 - P280 - P308 + P313 - P405
危险分类	Muta. 1B - Repr. 2 - STOT RE 2
储存分类代码	6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable