产品说明
特点和优势
Biotin-dPEG3-NH3+TFA- (Biotin-dPEG3-ammonium trifluoroacetate) reacts with activated esters (N-hydroxysuccinimide, 2,3,5,6-tetrafluorophenyl) of carboxylic acids under mildly basic conditions. It can be coupled directly to a carboxylic acid using 1-Ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) chemistry. Also, the product can react with carbonyl groups (aldehydes or ketones) to form a Schiff base. The Schiff base can be reduced to a secondary amine using sodium cyanoborohydride if additional conjugate stability is necessary. Biotin-dPEG3-NH3+TFA- can be used to biotinylate antibodies useful in western blotting and immunohistochemical applications.
法律信息
Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681
dPEG is a registered trademark of Quanta BioDesign
基本信息
经验(实验)分子式 | C22H39F3N4O7S |
分子量 | 560.63 |
产品性质
测定 | >95% (HPLC) |
形式 | solid or viscous liquid |
reaction suitability | reaction type: Biotinylations reaction type: Pegylations |
聚合物结构设计 | shape: linear functionality: monofunctional |
运输 | ambient |
储存温度 | −20℃ |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
Sigma-Aldrich