产品说明
生化/生理作用
Br-PBTC is a selective and potent type II positive allosteric modulator (PAM) that potentiates the opening of the nicotinic acetylcholine receptors (nAChR) subtypes containing α4β2, α2β2 and α2β4 subunits. Br-PBTC potentiates opening and reactivates desensitized (α4β2)2α4 nAChRs. It appears that Br-PBTC interacts with extracellular C-terminus of α2 or α4 in association with nearby parts of the α subunit.
基本信息
| 经验(实验)分子式 | C14H15BrN2OS |
| 分子量 | 339.25 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 颜色 | white to beige |
| 溶解性 | DMSO: 2 mg/mL, clear |
| 储存温度 | 2-8℃ |
| SMILES string | O=C(C1=CC(C=CC=C2Br)=C2S1)N[C@@H]3CCCNC3 |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
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