产品说明
一般描述
CD14 acts as a receptor for endotoxin (LPS), is expressed strongly on monocy¬tes, macrophages and weekly at surface of neutrophiles. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor LPS-LBP (lipopolysaccharide binding protein)-complexes. Furthermore CD14 is present in a soluble form in human serum, urine and other body fluids, acts at physiological concentrations as LPS agonist and has at higher concentrations an antagonizing effect in cell activation. The myeloid differentiation antigen CD14 acts as the major receptor for bacterial LPS. The dominant form of the recombinant wild type CD14 is the 50 kDa protein. This is a His-tagged protein.
外形
Lyophilized from a concentrated protein solution (1 mg/ml) containing PBS, pH 7.2
重悬
Centrifuge the vial prior to opening. Reconstitute in 10 μl of ultra-pure distilled water. This solution can then be diluted into other aqueous buffers.
基本信息
| NACRES | NA.32 |
产品性质
| 生物来源 | mouse |
| 重组 | expressed in CHO cells |
| 测定 | 90-95% (SDS-PAGE) |
| 形式 | lyophilized |
| 分子量 | 50.0 kDa |
| 包装 | pkg of 10 μg |
| 杂质 | Endotoxin, tested |
| NCBI登记号 | P10810 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | mouse ... CD14(12475) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
