产品说明
一般描述
Natural killer cell receptor 2B4 is also known as NK cell type I receptor protein 2B4 (NKR2B4 or h2B4), SLAM family member 4 (SLAMF4), Signaling lymphocytic activation molecule 4, CD antigen CD244. NKR2B4 / CD244 contain two Ig-like (immunoglobulin-like) domains. CD244 is expressed in spleen, PBL, followed by lung, liver, testis and small intestine. CD244 interacts with CD48. Following phosphorylation, CD244 is able to recruit PTPN11/SHP-2 and SH2D1A/SAP. SLAMF4 modulate other receptor-ligand interactions to enhance leukocyte activation. CD244/2B4 is the only heterophilic receptor of SLAM family.
外形
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.
重悬
Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/mL. Do not vortex. This solution can be stored at 2-8℃ for up to 1 month. For extended storage, it is recommended to store at -20℃.
基本信息
| NACRES | NA.32 |
产品性质
| 生物来源 | human |
| 重组 | expressed in HEK 293 cells |
| 标签 | 6-His tagged (C-terminus) |
| 测定 | ≥95% (SDS-PAGE) |
| 形式 | lyophilized |
| 分子量 | calculated mol wt 23.1 kDa observed mol wt 40-50 kDa (DTT-reduced. Protein migrates due to glycosylation. Cys 22 is the predicted N-terminus.) |
| 包装 | pkg of 10 μg pkg of 50 μg |
| UniProt登记号 | Q9BZW8 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... CD244(51744) |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
