产品说明
一般描述
CD40 Ligand (CD40L/TRAP) is a type II transmembrane glycoprotein belonging to the TNF superfamily of ligands. Natually, CD40L is a membrane-bound protein, but proteolytically cleaved 15-18 kDa soluble forms of CD40L are also fully active. CD40L plays an important role in the proliferation and differentiation of B-cells, and is critical for immunoglobulin (Ig) class switching. Recombinant mouse CD40 Ligand is a soluble 18 kDa protein containing 149 amino acid residues comprising the receptor binding TNF-like domain of CDE40L.
外形
Sterile filtered and then lyophilized from 10 mM Sodium Phosphate, pH 7.5 plus 0.1 M Arginine.
重悬
Reconstitute in water to a concentration of 0.1-1.0 mg/mL. The solution can then be diluted into other aqueous buffers.
Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.
基本信息
| NACRES | NA.32 |
产品性质
| 生物来源 | mouse |
| 重组 | expressed in E. coli |
| 测定 | ≥98% (HPLC) ≥98% (SDS-PAGE) |
| 形式 | lyophilized |
| 效能 | <0.1 μg/mL ED50 |
| 分子量 | ~16.4 kDa |
| 包装 | pkg of 25 μg |
| 储存条件 | avoid repeated freeze/thaw cycles |
| 杂质 | endotoxin, tested |
| NCBI登记号 | P27548 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | mouse ... Cd40lg(21947) |
Sigma-Aldrich
m.cnreagent.com
