产品说明
一般描述
CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two α chains, or a heterodimer composed of one α and one β chain. Both α and β chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 β chain isoforms. Recombinant human CD8B protein, fused to His-tag at N-terminus, was expressed in E.coli.
外形
0.5 mg/mL in 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea and 10% glycerol.
基本信息
| NACRES | NA.32 |
产品性质
| 生物来源 | human |
| 重组 | expressed in E. coli |
| 测定 | ≥80% (SDS-PAGE) |
| 形式 | liquid |
| 分子量 | 19.2 kDa (172 aa, 22-170 aa + His tag) |
| 包装 | pkg of 100 μg |
| 浓度 | 0.5 mg/mL |
| 杂质 | <1 EU/μg endotoxin (LAL test) |
| UniProt登记号 | P10966 |
| 运输 | dry ice |
| 储存温度 | −70℃ |
| Gene Information | human ... CD8B(926) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
