Cefiderocol

产品名称：

1225208-94-5
Cefiderocol

产品介绍：

产品说明

一般描述

Cefiderocol is a novel injectable siderophore cephalosporin, which was formerly known as S-649266.(1)(3) It has a catechol-type siderophore and cephalosporin core and side chains.(1) Cefiderocol has structural similarity with both ceftazidime and cefepime, besides the chlorocatechol group on the end of the C-3 chain.(2)

生化/生理作用

Cefiderocol has strong antimicrobial properties especially against a wide spectrum of Gram-negative pathogens.(1)(3) Due to its siderophore core, it is also a natural iron-chelator, which adds to its antibacterial activities.(1)

基本信息

经验(实验)分子式	C₃₀H₃₄ClN₇O₁₀S₂
分子量	752.21
MDL编号	MFCD30533432

产品性质

质量水平	100
测定	≥95% (HPLC)
抗生素抗菌谱	Gram-negative bacteria
作用机制	protein synthesis \| inhibits
储存温度	−20℃
SMILES string	NC1=NC(/C(C(N[C@@H]2C(N3[C@@H]2SCC(C[N+]4(CCCC4)CCNC(C5=CC=C(O)C(O)=C5Cl)=O)=C3C([O-])=O)=O)=O)=N/OC(C(O)=O)(C)C)=CS1