产品说明
一般描述
CK2α2 or casein kinase II alpha 2 is a member of the CK2 family of Ser/Thr protein kinases. CK2a2 plays a fundamental role in cell function and is involved in DNA replication, regulation of basal and inducible transcription, translation and control of metabolism. CK2α2 prefers utilization of acidic proteins such as caseins as substrates. The CK2a2 holoenzyme is a tetramer composed of an alpha chain, an alpha′ and two beta chains. The alpha and alpha′ chains contain the catalytic site. CK2α2 is also a component of CK2-SPT16-SSRP1 complex comprised of SSRP1, SUPT16H, CSNK2A1, CSNK2A2 and CSNK2B. This complex associates following UV irradiation. CK2a2 act as a candidate gene for inherited abnormalities of sperm morphogenesis.
外形
Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
制备说明
after opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles
法律信息
PRECISIO is a registered trademark of sigma-aldrich Co. LLC
基本信息
| NACRES | NA.32 |
产品性质
| 重组 | expressed in baculovirus infected Sf9 cells |
| 产品线 | PRECISIO® Kinase |
| 测定 | ≥70% (SDS-PAGE) |
| 形式 | buffered aqueous glycerol solution |
| specific activity | 63-72 nmol/min·mg |
| 分子量 | ~64 kDa |
| NCBI登记号 | NM_001896 |
| 运输 | dry ice |
| 储存温度 | −70℃ |
| Gene Information | human ... CSNK2A2(1459) |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
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