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CREB Binding Protein (1081-1197) GST tag human

品牌
Sigma-Aldrich
货号
SRP6576
规格纯度
recombinant, expressed in E. coli, ≥95% (SDS-PAGE)
参考价格
3817.59 *本价格含增值税费
促销
服务
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  • 增值税票
数量
-+
产品名称:
CREB Binding Protein (1081-1197) GST tag human
CREBBP
CBP
cAMP-responsive element-binding protein 1 CREB-1
产品介绍:

产品说明

一般描述

The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. A bromodomain is a protein domain that recognizes acetylated lysine residues such as those on the N-terminal tails of histones. This recognition is often a prerequisite for protein-histone association and chromatin remodeling. These domains function in the linking of protein complexes to acetylated nucleosomes, thereby controlling chromatin structure and gene expression. Thus, bromodomains serve as “readers” of histone acetylation marks regulating the transcription of target promoters. The cAMP response element-binding protein (CREB) binding protein (CREBBP) bromodomain has been shown to modulate the stability and function of the tumor suppressor protein p53. CREBBP bromodomain recognizes the acetylated lysine residue 382 on p53. This product contains the bromodomain region of CREBBP.

外形

50 mM Tris, pH 7.5, containing 500 mM sodium chloride, 5 mM β-mercaptoethanol and 5% glycerol.

基本信息

NACRESNA.32

产品性质

生物来源human
重组expressed in E. coli
测定≥95% (SDS-PAGE)
形式liquid
分子量 40.8 kDa (1081-1197 aa + NT GST Tag)
包装pkg of 20 and 100 μg
UniProt登记号Q92793
运输dry ice
储存温度−70℃
Gene Informationhuman ... CREB1(1385)

安全信息

象形图GHS07
警示用语:Warning
危险声明H317 - H319 - H412
预防措施声明P273 - P280 - P305 + P351 + P338 - P333 + P313 - P337 + P313
危险分类Aquatic Chronic 3 - Eye Irrit. 2 - Skin Sens. 1
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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