Dienogest

产品名称：

65928-58-7
Dienogest
17-Hydroxy-3-oxo-19-norpregna-4,9-diene-21-nitrile
17-Cyanomethyl-17-hydroxy-estra-4,9-dien-3-one
(17a)-17-Hydroxy-3-oxo-19-norpregna-4,9-diene-21-nitrile

产品介绍：

产品说明

包装

10, 50 mg in glass bottle

生化/生理作用

Dienogest is used to treat endometriosis. It might also help to decrease the levels of plasma estradiol by stimulating cell death of granulosa cells in the ovary.
Dienogest is a fourth-generation progestin, an orally active synthetic progestogen with approximately 10% of the relative affinity of progesterone, but has a very potent progestagenic effect in the endometrium with some antiandrogenic activity and without any androgenic, glucocorticoid or mineralocorticoid effects. It has been used alone or in combination as a contraceptive and to treat uterine fibroids. Dienogest inhibits ovulation primarily through peripheral action rather than by central action on gonadotrophin secretion.

基本信息

经验(实验)分子式	C₂₀H₂₅NO₂
分子量	311.42
MDL编号	MFCD00868356
PubChem化学物质编号	329825902
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
旋光性	[α]/D -305 to -325°, c = 1 in dichloromethane
颜色	white to beige
溶解性	DMSO: 5 mg/mL, clear (warmed)
储存温度	2-8℃
SMILES string	O[C@@]1(CC#N)CC[C@@]2([H])[C@]3([H])CCC4=CC(CCC4=C3CC[C@@]21C)=O
InChI	1S/C20H25NO2/c1-19-8-6-16-15-5-3-14(22)12-13(15)2-4-17(16)18(19)7-9-20(19,23)10-11-21/h12,17-18,23H,2-10H2,1H3/t17-,18+,19+,20-/m1/s1
InChI key	AZFLJNIPTRTECV-FUMNGEBKSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H361
预防措施声明	P280
危险分类	Repr. 2
储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable