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Dimethyl-L-arginine

品牌
Sigma-Aldrich
CAS
30315-93-6
货号
SMB00938
规格纯度
≥95% (HPLC)
参考价格
2236.58 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
产品名称:
30315-93-6
Dimethyl-L-arginine
Asymmetric dimethylarginine
(S)-2-Amino-5-(3,3-dimethylguanidino)pentanoic acid
产品介绍:

产品说明

一般描述

Asymmetric dimethylarginine (ADMA) is a naturally occurring chemical found in blood plasma. It is a metabolic by-product of continual protein modification processes in the cytoplasm of all human cells. It is closely related to L-arginine, a conditionally-essential amino acid. ADMA interferes with L-arginine in the production of nitric oxide, a key chemical to endothelial and hence cardiovascular health. Asymmetric dimethylarginine is created in protein methylation, a common mechanism of post-translational protein modification. This reaction is catalyzed by an enzyme set called S-adenosylmethionine protein N-methyltransferases (protein methylases I and II). The methyl groups transferred to create ADMA are derived from the methyl group donor S-adenosylmethionine, an intermediate in the metabolism of homocysteine. (Homocysteine is an important blood chemical, because it is also a marker of cardiovascular disease). After synthesis, ADMA migrates into the extracellular space and then into blood plasma.

应用

Metabolomics

基本信息

经验(实验)分子式C8H18N4O2
分子量202.25

产品性质

质量水平100
测定≥95% (HPLC)
形式powder
颜色 off-white

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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