产品说明
一般描述
DR6 is an orphan TNF receptor superfamily member belonging to a subgroup of receptors called death receptors. Expressed ubiquitously with high expression in lymphoid organs, heart, brain, and pancreas. Broadly expressed by developing neurons where it functions as pro-apoptotic factor. Recently, it has been reported that interaction with the beta-amyloid precursor protein (APP) activates a widespread caspase-dependent self-destruction program dependent on caspase-6.
外形
Lyophilized from PBS.
重悬
Reconstitute with 50 μL deionized water. Further dilutions should be made with medium containing 5% fetal calf serum or a carrier protein.
其他说明
The Fc portion of human IgG1 is fused to the C-terminus of human DR6 (aa 42-351).
基本信息
| NACRES | NA.32 |
产品性质
| 生物来源 | human |
| 重组 | expressed in HEK 293 cells |
| 测定 | >95% (SDS-PAGE) |
| 形式 | lyophilized |
| 分子量 | ~80 kDa by SDS-PAGE |
| 包装 | pkg of 50 μg |
| 储存条件 | avoid repeated freeze/thaw cycles |
| 杂质 | <0.1 EU/μg endotoxin, tested |
| 颜色 | white |
| UniProt登记号 | O75509 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... TNFRSF21(27242) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com