产品说明
生化/生理作用
Drotaverine (Drotaverin) is an isoquinoline-based PDE4-selective phosphodiesterase (PDE) inhibitor and an L-type voltage-dependent (voltage-operated) calcium channel (L-VDCC or L-VOCC) blocker that exhibits in vivo antispasmodic efficacy without anticholinergic effects.
It is a benzylisoquinoline derivative. Drotaverine acts as a smooth muscle relaxant.
基本信息
经验(实验)分子式 | C24H31NO4 · HCl |
分子量 | 433.97 |
MDL编号 | MFCD00347721 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
测定 | ≥95% (HPLC) |
形式 | powder |
储存条件 | desiccated |
颜色 | white to beige |
溶解性 | DMSO: 2 mg/mL, clear (warmed) |
储存温度 | 2-8℃ |
SMILES string | CCOC1=CC=C(/C=C2C3=C(CCN/2)C=C(OCC)C(OCC)=C3)C=C1OCC.[H]Cl |
InChI | 1S/C24H31NO4.ClH/c1-5-26-21-10-9-17(14-22(21)27-6-2)13-20-19-16-24(29-8-4)23(28-7-3)15-18(19)11-12-25-20;/h9-10,13-16,25H,5-8,11-12H2,1-4H3;1H/b20-13-; |
InChI key | JBFLYOLJRKJYNV-MASIZSFYSA-N |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H302 |
预防措施声明 | P301 + P312 + P330 |
危险分类 | Acute Tox. 4 Oral |
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich