Etravirine

产品名称：

269055-15-4
Etravirine
4-((6-Amino-5-bromo-2-((4-cyanophenyl)amino)pyrimidin-4-yl)oxy)-3,5-dimethylbenzonitrile
4-[[4-amino-5-bromo-6-(4-cyano-2,6-dimethylphenyloxy)-2-pyrimidinyl]amino]benzonitrile
4-[[6-Amino-5-bromo-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile
TMC125

产品介绍：

产品说明

生化/生理作用

Etravirine is a second-generation Nonnucleoside reverse transcriptase inhibitor (NNRTI) anti-retroviral. It is active against HIV with mutations that confer resistance to the two most commonly prescribed first-generation NNRTIs, mutation K103N for efavirenz and Y181C for nevirapine.

基本信息

经验(实验)分子式	C₂₀H₁₅BrN₆O
分子量	435.28
MDL编号	MFCD09837879

产品性质

测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 2 mg/mL, clear
储存温度	2-8℃
InChI	1S/C20H15BrN6O/c1-11-7-14(10-23)8-12(2)17(11)28-19-16(21)18(24)26-20(27-19)25-15-5-3-13(9-22)4-6-15/h3-8H,1-2H3,(H3,24,25,26,27)
InChI key	PYGWGZALEOIKDF-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H410
预防措施声明	P273
危险分类	Aquatic Acute 1 - Aquatic Chronic 1
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable