产品说明
一般描述
Inactive mutant version of our regular EZH2 5-member complex, but with a Tyr-to-Cys mutation on amino acids 646 of the EZH2 protein. Complex of human EZH2 (GenBank Accession No. NM_004456), (amino acids 2-end ; Y646C*) with N-terminal His-tag, MW= 86 kDa, human EED (GenBank Accession No. NM_003797) (amino acids 2-end) with N-terminal Flag-tag, MW= 51 kDa, human SUZ12 (GenBank Accession No. NM_015355) (amino acids 2-end) with N-terminal His-tag, MW = 87 kDa, Human AEBP2 (GenBank Accession No. NM_153207) (amino acids 2-end) with N-terminal His-tag, MW= 53 kDa, and human RbAp48 (GenBank Accession No. NM_005610) (amino acids 2-end) with N-terminal His-tag, MW = 48 kDa, coexpressed in Baculovirus expression system. *This mutation is often cited as Y641C in variant 3 (GenBank Accession No. NM_001203247).
基本信息
| NACRES | NA.32 |
产品性质
| 生物来源 | human |
| 重组 | expressed in baculovirus infected Sf9 cells |
| 测定 | ≥90% (SDS-PAGE) |
| 形式 | aqueous solution |
| 分子量 | 48 kDa (AEBP2) 51 kDa (EED) 53 kDa (AEBP2) 86 kDa (EZH2) 87 kDa (SUZ12) |
| 包装 | pkg of 20 μg |
| NCBI登记号 | NM_003797 (EED) NM_004456 (EZH2) NM_005610 (RbAP48) NM_015355 (SUZ12) NM_153207 (AEBP2) |
| 运输 | dry ice |
| 储存温度 | −70℃ |
| Gene Information | human ... EED(8726), EZH2(2146), RBBP4(5928), SUZ12(23512) |
安全信息
| 象形图 |   |
| 警示用语： | Danger |
| 危险声明 | H315 - H319 - H360D |
| 预防措施声明 | P202 - P264 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313 |
| 危险分类 | Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 |
| 储存分类代码 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
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