产品说明
一般描述
FGF12 (Fibroblast growth factor 12) is a member of the FGF superfamily of molecules which currently stands at 22 members. The FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. FGF12 binds to IB2 (islet brain-2), a cellular kinase scaffold, and voltage gated sodium channels and also plays an important role in intracellular signaling and ion exchange. Recombinant human FGF12 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
外形
1 mg/mL in 20 mM Tris pH 7.5, 10% glycerol, 1 mM DTT, 2 mM EDTA.
基本信息
| NACRES | NA.32 |
产品性质
| 生物来源 | human |
| 重组 | expressed in E. coli |
| 测定 | ≥90% (SDS-PAGE) |
| 形式 | liquid |
| 分子量 | 22.6 kDa (201 aa, 1-181 aa + His Tag) |
| 包装 | pkg of 50 μg |
| 浓度 | 1 mg/mL |
| UniProt登记号 | P61328 |
| 运输 | dry ice |
| 储存温度 | −70℃ |
| Gene Information | human ... FGF12(2257) |
安全信息
| 象形图 | ![]() |
| 警示用语: | Warning |
| 危险声明 | H319 |
| 预防措施声明 | P264 - P280 - P305 + P351 + P338 - P337 + P313 |
| 危险分类 | Eye Irrit. 2 |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |

Sigma-Aldrich
