产品说明
一般描述
TWEAK is a cytokine that controls proliferation, migration, differentiation, apoptosis, angiogenesis and inflammation. TWEAK binds to Fn14, a highly inducible cell-surface receptor that is linked to several intracellular signalling pathways, including the nuclear factor-B (NF-kappaB) pathway. The TWEAK-Fn14 axis plays a beneficial role in tissue repair following acute injury and may contribute to cancer, chronic autoimmune diseases and acute ischaemic stroke.
外形
Lyophilized from PBS.
重悬
Reconstitute with 50 μL deionized water.
其他说明
The extracellular region of human FN14 (aa 28-75) is fused at the C-terminus to the Fc portion of human IgG1.
基本信息
| NACRES | NA.32 |
产品性质
| 生物来源 | human |
| 重组 | expressed in HEK 293 cells |
| 测定 | >95% (SDS-PAGE) |
| 形式 | lyophilized |
| 分子量 | ~35 kDa by SDS-PAGE |
| 包装 | pkg of 50 μg |
| 储存条件 | avoid repeated freeze/thaw cycles |
| 杂质 | <0.1 EU/μg endotoxin, tested |
| 颜色 | white |
| UniProt登记号 | Q9NP84 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... TNFRSF12A(51330) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
