产品说明
包装
10, 50 mg in glass bottle
生化/生理作用
During migraine condition, frovatriptan succinate monohydrate acts on extra cerebral, intracranial arteries and prevent excessive dilation of these vessels.
Frovatriptan is a serotonin 5HT-1B/1D-receptor agonist used to treat migraine. Frovatriptan has high affinity for the 5-HT(1B) and 5-HT(1D) receptors while affinity for 5-HT receptors other than 5-HT(1B/1D) is substantially lower with a pEC50 value of 8.2 for the 5-HT1B receptor, compared to a pEC50 value of 6.2 for the 5-HT7 receptor.
基本信息
| 经验(实验)分子式 | C14H17N3O · C4H6O4 · H2O |
| 分子量 | 379.41 |
| MDL编号 | MFCD18251278 |
| PubChem化学物质编号 | 329825767 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥97% (HPLC) |
| 形式 | powder |
| 储存条件 | desiccated |
| 颜色 | white to beige |
| 溶解性 | H2O: 20 mg/mL, clear |
| 储存温度 | 2-8℃ |
| SMILES string | OC(CCC(O)=O)=O.NC(C(C=C1)=CC2=C1NC3=C2C[C@H](NC)CC3)=O.O |
| InChI | 1S/C14H17N3O.C4H6O4.H2O/c1-16-9-3-5-13-11(7-9)10-6-8(14(15)18)2-4-12(10)17-13;5-3(6)1-2-4(7)8;/h2,4,6,9,16-17H,3,5,7H2,1H3,(H2,15,18);1-2H2,(H,5,6)(H,7,8);1H2/t9-;;/m1../s1 |
| InChI key | CUETXFMONOSVJA-KLQYNRQASA-N |
| Gene Information | human ... HTR1B(3351), HTR1D(3352) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
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