产品说明
一般描述
FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse ‘fused toes′ mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol.
外形
0.5 mg/mL of 0.2 μm-filtered solution in 55 mM Tris-Cl, pH 8.2 containing 150 mM NaCl.
基本信息
NACRES | NA.32 |
产品性质
生物来源 | mouse |
重组 | expressed in E. coli |
测定 | ≥90% (SDS-PAGE) |
形式 | liquid |
分子量 | ~55 kDa (Mouse FTO aa 2-502 is fused at the N-terminus to a His-tag.) |
包装 | pkg of 10 μg |
浓度 | 0.5 mg/mL |
杂质 | <1 EU/μg endotoxin (LAL test) |
UniProt登记号 | Q8BGW1 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | mouse ... FTO(26383) |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich