产品说明
一般描述
FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse ′fused toes′ mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol.
外形
Solution in 55 mM TRIS-HCl, pH 8.2, containing 150 mM NaCl.
其他说明
Mouse FTO (aa 2-502) is fused at the N-terminus to a His-tag.
基本信息
| NACRES | NA.32 |
产品性质
| 生物来源 | mouse |
| 重组 | expressed in E. coli |
| 标签 | His tagged |
| 测定 | >90% (SDS-PAGE) |
| 形式 | liquid |
| 分子量 | ~55 kDa by SDS-PAGE |
| 包装 | pkg of 10 μg |
| 储存条件 | avoid repeated freeze/thaw cycles |
| 浓度 | ≥0.2 mg/mL |
| 杂质 | <1 EU/μg endotoxin, tested |
| 颜色 | clear |
| UniProt登记号 | Q8BGW1 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | mouse ... Fto(26383) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
Sigma-Aldrich
m.cnreagent.com
