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GITRL, Soluble mouse

品牌
Sigma-Aldrich
货号
SRP8009
规格纯度
recombinant, expressed in HEK 293 cells, FLAG® tagged, >90% (SDS-PAGE)
参考价格
7680.43 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
GITRL, Soluble mouse
TNFSF18
Glucocorticoid-induced TNF receptor ligand
AITRL
EGF-like protein 9
产品介绍:

产品说明

一般描述

GITRL (Glucocorticoid-induced TNF receptor ligand) is expressed on dendritic cells (DC), monocytes, macrophages, B cells, activated T cells, endothelial cells, osteoclasts and various healthy non-lymphoid tissues (e.g. testis). GITRL is constitutively expressed and released as soluble form by solid tumors and various hematopoietic malignancies. GITRL causes differentiation of osteoclasts, activation of macrophages, but also alteration of carcinoma and leukemia cells and influences apoptosis. Binding to GITR is important in regulating T cell proliferation and TCR-mediated apoptosis. GITRL is implicated in development of autoimmune diseases and in the immune response against infectious pathogens and tumors.

外形

Solution in 10 mM glycine, pH 10.0.

其他说明

The extracellular domain of mouse GITRL (aa 45-173) is fused at the N-terminus to a FLAG®-tag.

法律信息

FLAG is a registered trademark of sigma-aldrich Co. LLC

基本信息

NACRESNA.32

产品性质

生物来源mouse
重组expressed in HEK 293 cells
标签FLAG® tagged
测定>90% (SDS-PAGE)
形式liquid
分子量 ~22 kDa by SDS-PAGE
包装pkg of 50 μg
储存条件avoid repeated freeze/thaw cycles
浓度≥0.2 mg/mL
杂质<0.1 EU/μg endotoxin, tested
颜色 clear
UniProt登记号Q7TS55
运输wet ice
储存温度−20℃
Gene Informationmouse ... Tnfsf18(240873)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1

Sigma-Aldrich

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