产品说明
一般描述
GPX1 (glutathione peroxidase 1) is a selenoprotein and the gene is mapped to human chromosome 3p21.3. It is present in the cytoplasm and is widely expressed.
生化/生理作用
GPX1 (glutathione peroxidase 1) is responsible for scavenging free radicals and derivatives. GPXs reduces lipid hydroperoxides to the corresponding alcohols as well as free hydrogen peroxide to water. Mutations in the GPX1 gene are associated with nonalcoholic fatty liver disease (NAFLD) susceptibility. Mutation in GPX1 at C594T is linked with oxidative stress-associated disorders, including prostate cancer and bladder cancer.
外形
Lyophilized from 55 mM TRIS-HCl, pH 8.2, containing 150 mM NaCl, 1 mM DTT.
重悬
Reconstitute with 100 μL deionized water.
其他说明
Human GPX1 (aa 1-201) is fused at the C-terminus to a His-tag.
基本信息
| NACRES | NA.32 |
产品性质
| 生物来源 | human |
| 重组 | expressed in E. coli |
| 标签 | His tagged |
| 测定 | >90% (SDS-PAGE) |
| 形式 | lyophilized |
| 分子量 | ~25 kDa by SDS-PAGE |
| 包装 | pkg of 10 μg |
| 储存条件 | avoid repeated freeze/thaw cycles |
| 杂质 | <1 EU/μg endotoxin, tested |
| 颜色 | white |
| UniProt登记号 | P07203 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... GPX1(2876) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
Sigma-Aldrich
m.cnreagent.com
