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Granulocyte Elastase Substrate human

品牌
Sigma-Aldrich
货号
SCP0170
包装型号
规格纯度
参考价格
1510.01 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
产品名称:
Granulocyte Elastase Substrate human
产品介绍:

产品说明

Amino Acid Sequence

Glp-Pro-Val-pNA

一般描述

Elastase, a glycoprotein, is a member of the serine proteases family. It is synthesized by human polymorphonuclear (PMN) leukocytes or by the pancreas. Human granulocyte elastase is liberated in large amounts from granulocytes in chronic inflammatory joint disorders.

生化/生理作用

Elastase is a catalytic enzyme that catalyzes the cleavage of carboxyl groups on tiny hydrophobic amino acids including glycine, alanine, and valine. Its main function is to break down elastin. Free elastase in some purulent synovial fluids plays a key role in articular cartilage breakdown. Increased elastase levels in the plasma have been seen in patients with evident rheumatoid arthritis.
Elastase(s) can be assayed and differentiated using chromogenic and fluorogenic Pro-Val peptide substrates such as Glp-Pro-Val-pNA and MeOSuc-Ala-Ala-Pro-Val-4-MNA.

基本信息

经验(实验)分子式C21H27N5O6
分子量445.47
NACRESNA.32

产品性质

测定≥95% (HPLC)
形式lyophilized
组成Peptide Content, ≥85%
储存条件protect from light
储存温度−20℃

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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