产品说明
一般描述
Granzyme A is a member of the granzyme family. Granzyme A is the most abundant serine protease in cytotoxic T lymphocytes (CTL) and natural killer (NK) cells. Granzyme A has a specific function in CTL and NK cells. It induces caspase-independent cell death when introduced into target cells by perforin. Human granzyme A is synthesized as a precursor (262 residues) with a signal peptide (residues 1-26), a propeptide (residues 27-28) and a mature chain (residues 29-262).
外形
Lyophilized from a 0.2 μm filtered solution of 20 mM MES and150 mM NaCl, pH 5.5.
制备说明
Centrifuge the vial prior to opening.
重悬
Dissolve in 1x PBS (It is not recommended to reconstitute to a final concentration less than 100 μg/mL.). This can further be diluted to other aqueous buffers.
其他说明
Recombinant Human Granzyme A is produced with mammalian cells expression system. Target protein is expressed with sequence (Glu27-Val262) of Human granzyme a (Uniprot #P12544) fused with a polyhistidine tag at the C-terminus.
基本信息
| NACRES | NA.32 |
产品性质
| 生物来源 | human |
| 重组 | expressed in mammalian cells |
| 测定 | ≥95% (HPLC) ≥95% (SDS-PAGE) |
| 形式 | lyophilized |
| 分子量 | 26.9 kDa |
| 包装 | pkg of 10 μg |
| NCBI登记号 | P12544 |
| UniProt登记号 | P12544 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... GZMA(3001) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
