产品说明
一般描述
A fluorogenic, acetylated peptide substrate for HDAC′s. Based on residues 379-382 of p53, Arg-His-Lys-Lys, Ac, a site of regulatory acetylation by the p300 and CBP acetyltransferases, lysines 381, 382, 1-3, it is a suitable substrate for HDAC2, HDAC3, and HDAC6 tested so far.
应用
Study enzyme kinetics, and screen small molecule inhibitors for drug discovery and HTS applications.
外形
Supplied as a 5 mM solution in DMSO.
基本信息
| NACRES | NA.32 |
产品性质
| 测定 | ≥90% (HPLC) |
| 形式 | aqueous solution |
| 包装 | pkg of 500 nmol |
| 运输 | dry ice |
| 储存温度 | −70℃ |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | WGK 3 |
| 闪点(F) | 188.6 °F - closed cup |
| 闪点(C) | 87 ℃ - closed cup |
Sigma-Aldrich
m.cnreagent.com
