您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 品牌 > Sigma-Aldrich > Histone H4 peptide (1-21) human

Histone H4 peptide (1-21) human

品牌
Sigma-Aldrich
货号
SRP0161
规格纯度
≥90% (HPLC)
参考价格
3616.51 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Histone H4 peptide (1-21) human
HIST2H4A
产品介绍:

产品说明

应用

Study enzyme kinetics, and screen small molecular inhibitors of Histone 3 R3 methyltransferases for drug discovery and HTS applications

生化/生理作用

H4 (histone 4) is a core histone protein which is mobilized during herpes simplex virus 1 (HSV1) infection. This leads to elevated pools of free H2B and H4 and decreased rate of H2B fast chromatin exchange. Free H4 associates with HSV1 genomes, and this mobilization is also linked with the organization of H2A-H2B and H3-H4 dimers into unstable nucleosomes with HSV-1 genomes. The histone chaperone nuclear autoantigenic sperm protein (NASP) is responsible for maintaining a reservoir of soluble H3-H4 histones, where it regulates the activity of heat shock proteins Hsc70 and Hsp90, which target H3-H4 for degradation by chaperone-mediated autophagy. This reservoir level, in turn, depends upon the level of NASP.

外形

Supplied as water solution, 800 μM

制备说明

Thaw on ice. Upon first thaw, briefly spin tube to recover full content of the tube. Aliquot into single use aliquots. Store remaining product in aliquots at -70℃. Note: Avoid freeze/thaw cycles.

基本信息

NACRESNA.32

产品性质

生物来源human
测定≥90% (HPLC)
形式aqueous solution
分子量 ~2 kDa
包装pkg of 160 nmol
储存条件avoid repeated freeze/thaw cycles
浓度>0.02 mg/mL
NCBI登记号NM_003548
UniProt登记号P62805
运输dry ice
储存温度−70℃
Gene Informationhuman ... HIST2H4A(8370)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

推荐产品