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HSP90 α, His tagged human

HSP90 α,His 标记 人

品牌
Sigma-Aldrich
CAS
481150-77-0
货号
SRP5191
规格纯度
recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
参考价格
4311.28 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
481150-77-0
HSP90 α, His tagged human
FLJ31884
Hsp90
HSPN
HSP90N
HSP86
hspc1
hspca
LAP2
HSPCAL1
HSP90AA1
HSPCAL4
Hsp89
HSP90 α,His 标记 人
产品介绍:

产品说明

一般描述

Heat shock protein 90α (HSP90α) is a member of the HSP90 family of proteins which are important molecular chaperones involved in signal transduction, cell cycle control, stress management, folding, degradation, and transport of proteins. The gene encoding this protein is localized on human chromosome 14q32.31.

生化/生理作用

Heat shock protein 90α (HSP90α) is a molecular chaperone involved in the folding, assembly-disassembly and activation of multiple types of target proteins such as kinases, steroid hormone receptors and transcription factors. HSP90 inhibitors bind to HSP90, and induce the proteasomal degradation of HSP90 client proteins. HSP90α is an important mediator of cancer cell invasion and is expressed extracellularly on fibrosarcoma and breast cancer cells where it interacts with MMP2 (matrix metalloproteinase-2).

外形

Supplied in 50mM MOPS, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol.

制备说明

after opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles

基本信息

NACRESNA.32

产品性质

生物来源human
重组expressed in baculovirus infected Sf9 cells
测定≥70% (SDS-PAGE)
形式buffered aqueous glycerol solution
分子量 ~94 kDa
technique(s)cell culture | mammalian: suitable
NCBI登记号NM_005348
运输dry ice
储存温度−70℃
Gene Informationhuman ... HSP90AA1(3320)

安全信息

象形图GHS07GHS08
警示用语:Danger
危险声明H315 - H319 - H360D
预防措施声明P202 - P264 - P280 - P302 + P352 - P305 + P351 + P338 - P308 + P313
危险分类Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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