产品说明
一般描述
Chemical structure: Aminoglycoside
应用
Hygromycin B is an aminoglycoside antibiotic isolated from Streptomyces hygroscopicus. It has been used to study protein synthesis at the level of the 70S ribosome translocation and mRNA template misreading, as an antiviral agent by selectively penetrating cells rendered permeable by virus infection and inhibiting translation, and as a selection agent for hygromycin resistance gene transformed cells. It is recommended for use as a selection agent at 100-800 μg/mL, specifically at 100 μg/mL for prokaryotes, 200 μg/mL for lower eukaryotes and 150-400 μg/mL for higher eukaryotes.
生化/生理作用
Mode of Action: The product acts by inhibiting protein synthesis by inducing the misreading of the m-RNA template in the prokaryote, with the potency to inhibit translation.
特点和优势
Ready made solution for ease of use
基本信息
| 经验(实验)分子式 | C20H37N3O13 |
| 分子量 | 527.52 |
产品性质
| 质量水平 | 200 |
| 生物来源 | Streptomyces hygroscopicus |
| 浓度 | 50 mg/mL in water (from Streptomyces hygroscopicus) |
| 抗生素抗菌谱 | Gram-negative bacteria Gram-positive bacteria fungi viruses |
| 储存温度 | 2-8℃ |
安全信息
| 象形图 |  |
| 警示用语： | Danger |
| 危险声明 | H301 - H312 - H330 |
| 预防措施声明 | P260 - P264 - P270 - P280 - P302 + P352 + P312 - P304 + P340 + P310 |
| 危险分类 | Acute Tox. 1 Inhalation - Acute Tox. 3 Oral - Acute Tox. 4 Dermal |
| 储存分类代码 | 6.1B - Non-combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
