产品说明
一般描述
Intercellular adhesion molecule 2 (ICAM2) is also known as CD antigen CD102, which belongs to the immunoglobulin superfamily and ICAM family. ICAM2 contains two Ig-like C2-type (immunoglobulin-like) domains. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin α-L/β-2). ICAM2 / CD102 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response; NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.
外形
Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally Mannitol or Trehalose is added as protectants before lyophilization.
重悬
Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/mL. Do not vortex. This solution can be stored at 2-8℃ for up to 1 month. For extended storage, it is recommended to store at -20℃.
基本信息
NACRES | NA.32 |
产品性质
生物来源 | human |
重组 | expressed in HEK 293 cells |
标签 | 6-His tagged (C-terminus) |
测定 | ≥95% (SDS-PAGE) |
形式 | lyophilized |
分子量 | calculated mol wt 23.3 kDa observed mol wt 40-63 kDa (DTT-reduced. Protein migrates due to glycosylation. Ser 22 is the predicted N-terminal.) |
包装 | pkg of 10 and 50 μg |
杂质 | <1 EU/μg endotoxin (LAL test) |
UniProt登记号 | P13598 |
运输 | wet ice |
储存温度 | −20℃ |
Gene Information | human ... ICAM2(3384) |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich