4-吡啶羧酸酰肼

产品名称：

54-85-3
Isoniazid
INH
4-Pyridinecarboxylic acid hydrazide
Isonicotinic Acid Hydrazide
Isonicotinic hydrazide
异烟肼
雷米封
4-吡啶羧酸酰肼
异烟酸肼

产品介绍：

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

针对结核菌的抗生素，抑制分枝菌酸的生物合成。由肝脏 N-乙酰转移酶 (NAT) 和细胞色素 P450 2E1 (CYP2E1) 代谢形成肝毒素。选择性诱导 CYP2E1 的表达。可逆抑制 CYP2C19 和 CYP3A4 的活性，在临床相关浓度下机械性地灭活 CYP1A2、CYP2A6、CYP2C19 和 CYP3A4。

包装

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式	C₆H₇N₃O
分子量	137.14
Beilstein	119374
MDL编号	MFCD00006426

产品性质

等级	pharmaceutical primary standard
manufacturer/tradename	BP
mp	171-173 ℃ (lit.)
格式	neat
储存温度	2-8℃
SMILES string	NNC(=O)c1ccncc1
InChI	1S/C6H7N3O/c7-9-6(10)5-1-3-8-4-2-5/h1-4H,7H2,(H,9,10)
InChI key	QRXWMOHMRWLFEY-UHFFFAOYSA-N