Jagged-2 (human): FC (human)

产品名称：

Jagged-2 (human): FC (human)
Protein jagged-2
Alpha-ketoglutarate-dependent dioxygenase FTO
hJ2

产品介绍：

产品说明

一般描述

Jagged-2 is a putative Notch ligand involved in the mediation of Notch signaling, that can induce stromal cells to secrete IL-6, VEGF and IGF-1. Notch activation can interact with NF-kappaB and C-myc to promote the proliferation and to inhibit the apoptosis of MM cells, showing in the relationship between the incidence of myeloma and drug resistance. Jagged-2 is also involved in limb development.

序列

Human Jagged-2 (aa 1-1054) is fused at the C-terminus to the Fc portion of human IgG.

外形

Lyophilized. Contains PBS + 0.02 % CHAPS.

重悬

Reconstitute with 100μl sterile water.

基本信息

NACRES

NA.32

产品性质

重组	expressed in HEK 293 cells
测定	≥90% (SDS-PAGE)
形式	lyophilized
分子量	~150 kDa by SDS-PAGE
杂质	<0.1 EU/μgtested
UniProt登记号	Q9Y219
运输	wet ice
储存温度	−20℃
Gene Information	human ... JAG2(3714)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable