产品说明
一般描述
NKG2-C type II integral membrane protein, also known as KLRC2, plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. KLRC2 alternative splice variants have been described but their full-length nature has not been determined. Recombinant human KLRC2 protein, fused to His-tag at N-terminus, was expressed in E.coli.
外形
0.5 mg/mL in 20 mM Tris-HCl buffer (pH 8.0) containing 0.4 M Urea and 10% glycerol.
基本信息
| NACRES | NA.32 |
产品性质
| 生物来源 | human |
| 重组 | expressed in E. coli |
| 测定 | ≥85% (SDS-PAGE) |
| 形式 | liquid |
| 分子量 | 18.4 kDa (162 aa, 94-231 aa + His Tag) |
| 包装 | pkg of 50 μg |
| 浓度 | 0.5 mg/mL |
| UniProt登记号 | P26717 |
| 运输 | dry ice |
| 储存温度 | −70℃ |
| Gene Information | human ... KLRC2(3822) |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
