产品说明
一般描述
Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.
外形
Solution in PBS.
其他说明
The sequence coding for the 4 extracellular Ig-like domains of mouse LAG-3 (D1-D4) is fused to the Fc portion of mouse IgG2a (hinge-CH2-CH3).
基本信息
| NACRES | NA.32 |
产品性质
| 生物来源 | mouse |
| 重组 | expressed in CHO cells |
| 测定 | >95% (SDS-PAGE) |
| 形式 | liquid |
| 分子量 | monomer ~180 kDa by SDS-PAGE (non-reducing) monomer ~80 kDa by SDS-PAGE (reducing) |
| 包装 | pkg of 50 μg |
| 储存条件 | avoid repeated freeze/thaw cycles |
| 浓度 | ≥0.2 mg/mL |
| 杂质 | <1 EU/μg endotoxin, tested |
| 颜色 | clear |
| UniProt登记号 | Q61790 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | mouse ... Lag3(16768) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
