产品说明
应用
Lazabemide hydrate may be used in cell signaling studies.
包装
10, 50 mg in glass bottle
生化/生理作用
Lazabemide is effective in treatment of Alzheimer′s disease and in combination with nicotine replacement therapy aids in smoking cessation.
Lazabemide is a selective and reversible monoamine oxidase B (MAO-B) inhibitor and Anti-Parkinson. Also it inhibits monoamine uptake at high concentrations (IC50 values are 86, 123 and > 500 μM for noradrenalin, serotonin and dopamine uptake respectively).
特点和优势
This compound is featured on the Dopamine and Norepinephrine Metabolism and Histamine Synthesis and Metabolism pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
基本信息
| 经验(实验)分子式 | C8H10ClN3O · xH2O |
| 分子量 | 199.64 (anhydrous basis) |
| MDL编号 | MFCD20488051 |
| PubChem化学物质编号 | 329825112 |
| NACRES | NA.77 |
产品性质
| 质量水平 | 100 |
| 测定 | ≥97% (HPLC) |
| 形式 | powder |
| 储存条件 | desiccated |
| 颜色 | white to tan |
| 溶解性 | DMSO: ≥22 mg/mL |
| 创始人 | Roche |
| 储存温度 | room temp |
| SMILES string | O.NCCNC(=O)c1ccc(Cl)cn1 |
| InChI | 1S/C8H10ClN3O.H2O/c9-6-1-2-7(12-5-6)8(13)11-4-3-10;/h1-2,5H,3-4,10H2,(H,11,13);1H2 |
| InChI key | JYWYNPKXSLPWGV-UHFFFAOYSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Warning |
| 危险声明 | H302 - H319 |
| 预防措施声明 | P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 - P337 + P313 |
| 危险分类 | Acute Tox. 4 Oral - Eye Irrit. 2 |
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
