产品说明
包装
10, 50 mg in glass bottle
生化/生理作用
Lesinurad is a selective inhibitor of Urate transporter 1 (URAT1), a urate-anion exchanger which is responsible for the majority of uric acid reabsorption from the renal tubular lumen. Lesinurad thus reduces serum uric acid levels. Lesinurad has been approved for use in combination with a xanthine oxidase inhibitor to treat hyperuricemia associated with gout.
基本信息
经验(实验)分子式 | C17H14BrN3O2S |
分子量 | 404.28 |
MDL编号 | MFCD22572730 |
PubChem化学物质编号 | 329825493 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | powder |
颜色 | white to beige |
溶解性 | DMSO: 25 mg/mL, clear |
储存温度 | −20℃ |
SMILES string | BrC1=NN=C(SCC(O)=O)N1C2=C3C(C=CC=C3)=C(C4CC4)C=C2 |
InChI | 1S/C17H14BrN3O2S/c18-16-19-20-17(24-9-15(22)23)21(16)14-8-7-11(10-5-6-10)12-3-1-2-4-13(12)14/h1-4,7-8,10H,5-6,9H2,(H,22,23) |
InChI key | FGQFOYHRJSUHMR-UHFFFAOYSA-N |
Gene Information | human ... SLC22A12(116085) |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich