产品说明
生化/生理作用
A selective inhibitor of the p70 ribosomal S6 kinase (S6K). Blocks the phosphorylation of S6 at concentrations as low as 0.1-0.3 uM with no activity at GSK3beta and Erk1/2 at 10 uM (2). Useful tool to dissect insulin receptor signaling pathways and was employed to show that the action of mTORC1 on SREB P-1c expression is not mediated by S6K. Cell permeable.
重悬
Formulated as a lyophilized powder. May be dissolved in DMSO (1 mg/mL) or DMF (3 mg/mL, warm).
储存及稳定性
Store desiccated as supplied at -20℃ for up to 3 years. Store solutions at -20℃ for up to 3 months.
产品性质
| 测定 | >95% (HPLC) |
| 形式 | lyophilized powder |
| 分子量 | ~445.4 |
| 运输 | ambient |
| 储存温度 | −20℃ |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
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