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m-dPEG®37-NHS ester

品牌
Sigma-Aldrich
货号
QBD10910
包装型号
规格纯度
>95% (HPLC)
参考价格
4445.62 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
m-dPEG®37-NHS ester
mPEG1500-NHS ester
m-PEG37-NHS ester
mPEG37-NHS ester
mPEG-NHS ester
产品介绍:

产品说明

特点和优势

m-dPEG37-NHS ester is a methyl-terminated, single molecular weight, discrete chain length polyethylene glycol (dPEG) spacer. The carboxylic acid moiety on the end of the molecule opposite the methyl cap is activated with N-hydroxysuccinimide (NHS) for facile reaction with free amines. The dPEG spacer is 112 atoms (133.9 Å) long, a monodisperse equivalent of a polymeric PEG1500. m-dPEG37-NHS ester can be used to modify silica shelled quantum dots to make them water-soluble. Also, it has been employed to improve the pharmacokinetic (PK) and biodistribution (BD) properties of an antibody. Carbon nanotubes and inorganic nanoparticles with amine-functionalized surfaces could also be modified to passivate the surface and make it hydrophilic. Overall, proteins and other biomolecules conjugated to this product will have higher water solubility, reduced or eliminated antigenicity, and improved PK and BD properties.

法律信息

Products Protected under U.S. Patent #s 7,888,536 & 8,637,711 and European Patent #s 1,594,440 & 2,750,681
dPEG is a registered trademark of Quanta BioDesign

基本信息

经验(实验)分子式C80H155NO41
分子量1787.07
MDL编号MFCD21363217

产品性质

测定>95% (HPLC)
形式solid or viscous liquid
reaction suitabilityreaction type: Pegylations
聚合物结构设计shape: linear
functionality: monofunctional
运输ambient
储存温度−20℃

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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