产品说明
特点和优势
The m-dPEG®8-MAL provides a variety of means to modify small molecules, peptides, proteins, and functionalized surfaces (metals, glass, and others). The single molecular weight methoxy-terminated dPEG® molecules are hydrophilic and non-immunogenic of exact length. Modification with m-dPEG® reagents can improve water solubility, increase hydrodynamic volume, eliminate or reduce non-specific binding, protect peptides and proteins from proteolysis, reduce or eliminate immunogenicity, and increase serum half-life in vivo. The m-dPEG®8-MAL reacts with free sulfhydryls in a rapid, highly specific reaction in aqueous media at pH 6.5-7.5.
法律信息
Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign
基本信息
经验(实验)分子式 | C24H42N2O11 |
分子量 | 534.60 |
MDL编号 | MFCD13185021 |
PubChem化学物质编号 | 329823947 |
NACRES | NA.22 |
产品性质
测定 | >90% |
形式 | solid or viscous liquid |
reaction suitability | reagent type: chemical modification reagent reactivity: sulfhydryl reactive reagent type: chemical modification reagent reactivity: thiol reactive reagent type: cross-linking reagent |
聚合物结构设计 | shape: linear functionality: monofunctional |
运输 | ambient |
储存温度 | −20℃ |
SMILES string | COCCOCCOCCOCCOCCOCCOCCOCCNC(CCN1C(C=CC1=O)=O)=O |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich