产品说明
特点和优势
MAL-dPEG®4-(m-dPEG®12)3 is a branched dPEG® reagent which is highly useful for protein and peptide modification to increase hydrodynamic volume and serum half-life and to greatly reduce the immunogenicity of the modified peptide or protein. This dPEG® product consists of a linear "tail" with a reactive group, a tris core to provide branching, and methoxy-terminated dPEG® branches. The numbers following dPEG® are the exact number of repeat units in the linear chain. All of these dPEG® products are hydrophilic, non-immunogenic, single molecular weight compounds. The maleimide functional group reacts rapidly and specifically with free sulfhydryls in aqueous media at pH 6.5-7.5.
法律信息
Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign
基本信息
经验(实验)分子式 | C106H202N6O50 |
分子量 | 2360.75 |
PubChem化学物质编号 | 329823926 |
NACRES | NA.22 |
产品性质
测定 | >90% |
形式 | solid or viscous liquid |
reaction suitability | reagent type: chemical modification reagent reactivity: sulfhydryl reactive reagent type: chemical modification reagent reactivity: thiol reactive reagent type: cross-linking reagent |
聚合物结构设计 | shape: branched functionality: monofunctional |
运输 | ambient |
储存温度 | −20℃ |
SMILES string | O=C(CCOCCOCCOCCOCCNC(CCN1C(C=CC1=O)=O)=O)NC(COCCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)(COCCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)COCCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich