产品说明
一般描述
Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the ′beads on a string′ structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.
特异性
Broad species cross-reactivity is expected based on sequence homology.
免疫原
KLH-conjugated, synthetic 2X-branched peptide corresponding to histone H3 monomethylated at lysine 9.
Epitope: methylated lysine 9
应用
Research Sub Category
Histone Modifying Proteins
Histones
Research Category
Epigenetics & Nuclear Function
Epigenetics & Nuclear Function
Detect monomethyl-Histone H3 (Lys9) using this Milli-Mark Anti-monomethyl-Histone H3 (Lys9)-FITC Antibody validated for use in FC.
质量
Evaluated by flow cytometry using HeLa cells.
目标描述
16 kDa Calculated
外形
Purified rabbit polyclonal IgG conjugated to FITC in PBS with 0.1% sodium azide and 15 mg/mL BSA.
Protein A purified
储存及稳定性
Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.
分析说明
Control
HeLa cells
法律信息
MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
偶联物 | FITC conjugate |
抗体形式 | purified immunoglobulin |
antibody product type | primary antibodies |
克隆 | polyclonal |
species reactivity | human |
manufacturer/tradename | Milli-Mark® |
technique(s) | flow cytometry: suitable |
同位素/亚型 | IgG |
NCBI登记号 | NP_003484 |
UniProt登记号 | Q16695 |
运输 | wet ice |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich