产品说明
包装
5, 25 mg in glass bottle
生化/生理作用
ML-161 is an antagonist of the protease-activated receptor 1 (PAR1), that inhibits thrombin and SFLLN-induced platelet activation. ML-161 dose dependently inhibits SFLLN-induced expression of P-selectin with an IC50 of 0.26 μM.
基本信息
经验(实验)分子式 | C17H17BrN2O2 |
分子量 | 361.23 |
MDL编号 | MFCD03063772 |
PubChem化学物质编号 | 329825413 |
NACRES | NA.77 |
产品性质
质量水平 | 100 |
测定 | ≥98% (HPLC) |
形式 | powder |
颜色 | white to beige |
溶解性 | DMSO: 5 mg/mL (clear solution) |
储存温度 | 2-8℃ |
SMILES string | CCCC(=O)Nc1cccc(NC(=O)c2ccccc2Br)c1 |
InChI | 1S/C17H17BrN2O2/c1-2-6-16(21)19-12-7-5-8-13(11-12)20-17(22)14-9-3-4-10-15(14)18/h3-5,7-11H,2,6H2,1H3,(H,19,21)(H,20,22) |
InChI key | DFOVLSMXPWPCFH-UHFFFAOYSA-N |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H410 |
预防措施声明 | P273 - P501 |
危险分类 | Aquatic Acute 1 - Aquatic Chronic 1 |
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich