产品说明
一般描述
AIFM1 (apoptosis inducing factor mitochondria associated 1) codes for apoptosis-inducing factor 1(AIF). It is located on human chromosome Xq26.1. AIF is a caspase-independent cell death effector.
免疫原
Purified recombinant fragment of human AIF expressed in E.coli.
Mouse monoclonal antibody raised against AIF
生化/生理作用
AIFM1 (apoptosis inducing factor mitochondria associated 1) possesses redox activity, which helps in oxidative phosphorylation. In the mitochondria, AIFM1 helps in assembling or maintaining the mitochondrial respiratory complexes I and III. It plays a vital role in apoptosis. This gene is associated with COXPD6 (combined oxidative phosphorylation deficiency, encephalomyopathy, Cowchock syndrome and X-linked deafness with neuropathy.
外形
Ascitic fluid containing 0.03% sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 质量水平 | 100 |
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| 抗体形式 | ascites fluid |
| antibody product type | primary antibodies |
| 克隆 | 4E7, monoclonal |
| 分子量 | 67 kDa |
| species reactivity | mouse, monkey, rat, human |
| technique(s) | direct ELISA: 1:10,000 flow cytometry: 1:200-1:400 immunohistochemistry: 1:200-1:1,000 indirect immunofluorescence: 1:200-1:1,000 western blot: 1:500-1:2,000 |
| 同位素/亚型 | IgG2b |
| NCBI登记号 | NM_001130846 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... AIF(9131) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
