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Monoclonal Anti-BLNK antibody produced in mouse

品牌
Sigma-Aldrich
货号
SAB1402572
规格纯度
clone 1D7, purified immunoglobulin, buffered aqueous solution
参考价格
5045.46 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
产品名称:
Monoclonal Anti-BLNK antibody produced in mouse
LY57
SLP65
MGC111051
BASH
SLP-65
BLNK-S
产品介绍:

产品说明

一般描述

This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq)

免疫原

BLNK (AAH18906, 301 a.a. ~ 400 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
KQIHQKPIPLPRFTEGGNPTVDGPLPSFSSNSTISEQEAGVLCKPWYAGACDRKSAEEALHRSNKDGSFLIRKSSGHDSKQPYTLVVFFNKRVYNIPVRF

外形

Solution in phosphate buffered saline, pH 7.4

基本信息

MDL编号MFCD02262572
NACRESNA.41

产品性质

质量水平100
生物来源mouse
偶联物unconjugated
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆1D7, monoclonal
形式buffered aqueous solution
分子量antigen ~37.11 kDa
species reactivityhuman
technique(s)indirect ELISA: suitable
proximity ligation assay: suitable
western blot: 1-5 μg/mL
同位素/亚型IgG2aκ
NCBI登记号BC018906
UniProt登记号Q8WV28
运输dry ice
储存温度−20℃
Gene Informationhuman ... BLNK(29760)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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