产品说明
一般描述
Monoclonal Anti- BOP1 (rat IgG1 isotype) is derived from the hybridoma BOP 6H11 produced by the fusion of mouse myeloma cells (P3X63Ag8.653) and splenocytes from rat immunized with a peptide corresponding to a fragment of human BOP1, coupled to ovalbumin.
应用
Monoclonal Anti-BOP1 antibody produced in rat has been used in several immunochemical techniques including immunoblotting, immunoprecipitation, and immunocytochemistry.
生化/生理作用
Ribosome biogenesis protein BOP1 is an essential component of A nucleolar complex, PeBoW that is involved in ribosome biogenesis and cell proliferation. Fluctuations in Bop1 protein level were found to affect the assembly and integrity of the whole PeBoW (Pes1, Bop1, and WDR12) complex. Overexpression of Bop1 mRNA is associated with the development of colorectal cancer.
外形
Solution in 0.01M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rat |
| 偶联物 | unconjugated |
| 抗体形式 | purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | BOP 6H11, monoclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen ~100 kDa |
| species reactivity | human |
| 包装 | antibody small pack of 25 μL |
| 浓度 | ~1.0 mg/mL |
| technique(s) | immunocytochemistry: suitable immunoprecipitation (IP): suitable western blot: 0.5-1.0 μg/mL using HeLa cell extracts |
| UniProt登记号 | Q14137 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... BOP1(23246) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
