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Monoclonal Anti-CAMLG, (N-terminal) antibody produced in mouse

品牌
Sigma-Aldrich
货号
SAB1402137
规格纯度
clone 3F12, purified immunoglobulin, buffered aqueous solution
参考价格
5045.46 *本价格含增值税费
促销
服务
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数量
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产品名称:
Monoclonal Anti-CAMLG, (N-terminal) antibody produced in mouse
CAML
MGC163197
产品介绍:

产品说明

一般描述

The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. (provided by RefSeq)

免疫原

CAMLG (NP_001736, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MESMAVATDGGERPGVPAGSGLSASQRRAELRRRKLLMNSEQRINRIMGFHRPGSGAEEESQTKSKQQDSDKLNSLSVPSVSKRVVLGDSVSTGTTDQQG

外形

Solution in phosphate buffered saline, pH 7.4

产品性质

质量水平100
生物来源mouse
偶联物unconjugated
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆3F12, monoclonal
形式buffered aqueous solution
分子量antigen ~37.11 kDa
species reactivityhuman
technique(s)capture ELISA: suitable
immunofluorescence: suitable
indirect ELISA: suitable
western blot: 1-5 μg/mL
同位素/亚型IgG2bκ
NCBI登记号NM_001745
UniProt登记号P49069
运输dry ice
储存温度−20℃
Gene Informationhuman ... CAMLG(819)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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