产品说明
一般描述
CD8 (cluster of differentiation 8), is a dimeric protein, encoded by the CD8A gene mapped to human chromosome 2p12. Human soluble CD8 (sCD8) is produced by activated CD8+ T lymphocytes.
免疫原
Crude thymus membrane fraction
应用
The reagent is designed for Flow Cytometry analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 1e6 cells in a suspension. The content of a vial (2 mL) is sufficient for 100 tests.
生化/生理作用
CD8 (cluster of differentiation 8) acts as a vital co-receptor of cytotoxic T cells. Mutation in the gene has been associated with the development of respiratory infections. Soluble CD8 plays a major role in regulation of soluble human leucocyte antigen I (sHLA-I) mediated transfusion-related immunomodulation (TRIM). Elevated levels of sCD8 has been observed in polytransfused patients suffering from human immunodeficiency virus-negative haemophilia and
特点和优势
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外形
Solution in phosphate buffered saline containing 15 mM sodium azide and 0.2% high-grade protease free BSA as a stabilizing agent.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
NACRES | NA.44 |
产品性质
质量水平 | 100 |
生物来源 | mouse |
偶联物 | phycoerythrin (R-PE) conjugate |
抗体形式 | purified immunoglobulin |
antibody product type | primary antibodies |
克隆 | MEM-31, monoclonal |
形式 | buffered aqueous solution |
species reactivity | human |
technique(s) | flow cytometry: suitable |
同位素/亚型 | IgG2a |
NCBI登记号 | NM_001145873.1 |
运输 | wet ice |
储存温度 | 2-8℃ |
Gene Information | human ... CD8(925) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich