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Monoclonal Anti-CD1b antibody produced in mouse

品牌
Sigma-Aldrich
货号
SAB1402712
规格纯度
clone 2E4, purified immunoglobulin, buffered aqueous solution
参考价格
6644.93 *本价格含增值税费
促销
服务
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  • 包邮
  • 增值税票
数量
-+
产品名称:
Monoclonal Anti-CD1b antibody produced in mouse
MGC125991
CD1A
MGC125990
CD1
R1
产品介绍:

产品说明

一般描述

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens. (provided by RefSeq)

免疫原

CD1B (NP_001755.1, 19 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
EHAFQGPTSFHVIQTSSFTNSTWAQTQGSGWLDDLQIHGWDSDSGTAIFLKPWSKGNFSDKEVAELEEIFRVYIFGFAREVQDFAGDFQMKY

应用

Monoclonal Anti-CD1B antibody produced in mouse is suitable for capture ELISA and indirect ELISA.

生化/生理作用

CD1B (CD1b molecule) is majorly involved in the glycolipid antigen recognition and presentation on the CD1b-restricted T Cells during the T cell-mediated immune responses. The antigen-binding groove directly links to the acyl chains of lipid antigens, which allows the hydrophilic components to interact with T cell antigen receptors.

外形

Solution in phosphate buffered saline, pH 7.4

基本信息

NACRESNA.41

产品性质

质量水平100
生物来源mouse
偶联物unconjugated
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆2E4, monoclonal
形式buffered aqueous solution
分子量antigen ~36.23 kDa
species reactivityhuman
technique(s)capture ELISA: suitable
indirect ELISA: suitable
同位素/亚型IgG2aκ
NCBI登记号NM_001764
UniProt登记号P29016
运输dry ice
储存温度−20℃
Gene Informationhuman ... CD1B(910)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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