产品说明
免疫原
CUEDC1 (NP_060419.1, 1 a.a. ~ 386 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MTSLFRRSSSGSGGGGTAGARGGGGGTAAPQELNNSRPARQVRRLEFNQAMDDFKTMFPNMDYDIIECVLRANSGAVDATIDQLLQMNLEGGGSSGGVYEDSSDSEDSIPPEILERTLEPDSSDEEPPPVYSPPAYHMHVFDRPYPLAPPTPPPRIDALGSGAPTSQRRYRNWNPPLLGNLPDDFLRILPQQLDSIQGNAGGPKPGSGEGCPPAMAGPGPGDQESRWKQYLEDERIALFLQNEEFMKELQRNRDFLLALERDRLKYESQKSKSSSVAVGNDFGFSSPVPGTGDANPAVSEDALFRDKLKHMGKSTRRKLFELARAFSEKTKMRKSKRKHLLKHQSLGAAASTANLLDDVEGHACDEDFRGRRQEAPKVEEGLREGQ
生化/生理作用
CUEDC1 (CUE domain containing 1) might be involved in protein trafficking and degradation. Changes in this gene are linked with early stage cervical cancer. It is highly methylated in the placental tissue of preeclampsia patients. CUEDC1 is suggested to control trophoblast invasion by participating in the TGF (transforming growth factor)-β/Smad (mothers against decapentaplegic homolog) signaling pathway. The gene is mapped to human chromosome 17q23.
外形
Solution in phosphate buffered saline, pH 7.4
基本信息
| NACRES | NA.41 |
产品性质
| 质量水平 | 100 |
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| 抗体形式 | purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | 4F9, monoclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen 68.7 kDa |
| species reactivity | human |
| technique(s) | indirect ELISA: suitable western blot: 1-5 μg/mL |
| 同位素/亚型 | IgG2aκ |
| NCBI登记号 | NM_017949.1 |
| UniProt登记号 | Q9NWM3 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... CUEDC1(404093) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
